We have completed this project, having added to it an additional experiment to confirm results and assessment of ‘Ca. L. asiaticus’ bacterial titers in all studies. In summary we find: · Both originally proposed studies were completed, as well as an additional confirmatory study with both oxytetracycline and streptomycin.· No foliar application treatment achieved a significant systemic delivery or oxytetracycline or streptomycin, nor did any reduce ‘Ca. L. asiaticus’ titer. · Injection of oxytetracycline exceeded the minimum effective concentration (MEC) and was greater than all adjuvants, and reduced ‘Ca. L. asiaticus’ titer.· Injection of streptomycin at the equivalent per-tree rate to labeled foliar application rates did not exceed MEC, nor did it affect ‘Ca. L. asiaticus’ titer.· Results indicate that: o Adjuvants to not enhance delivery of oxytetracycline or streptomycin sufficiently to impact ‘Ca. L. asiaticus’ titer at labeled rates. o Once delivered inside the plant, insufficient streptomycin moves systemically to impact ‘Ca. L. asiaticus’ titer at the equivalent per tree dose to the labeled per-acre equivalent. PublicationKilliny, N., Hijaz, F., Gonzalez-Blanco, P., Jones, S. E., Pierre, M. O., & Vincent, C. I. (2020). Effect of Adjuvants on Oxytetracycline Uptake upon Foliar Application in Citrus. Antibiotics, 9(10), 677. One additional manuscript presenting the findings of studies 2 and 3 is in preparation. A full report is submitted in a separate pdf.